Watson Institute for International and Public Affairs

Adam C. Levine, MD, MPH

adam_levine@brown.edu
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Claverick 274

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Adam C. Levine, MD, MPH

Associate Professor of Emergency Medicine

Biography

Adam Levine is an Associate Professor of Emergency Medicine at the Warren Alpert Medical School of Brown University and Director of the Brown University Global Emergency Medicine Fellowship. He received his Medical Doctorate from the University of California, San Francisco and his Masters of Public Health from the University of California, Berkeley before completing his specialty training in Emergency Medicine at the Harvard Affiliated Emergency Medicine Residency in Boston.

In recent years, Dr. Levine has responded to humanitarian emergencies in Haiti, Libya, South Sudan, and Liberia and has led research and training initiatives in Zambia, Bangladesh, Rwanda, Liberia and Sierra Leone. He currently serves as the Emergency Medicine Coordinator for the USAID-funded Human Resources for Health Program, helping to develop the first Emergency Medicine training program in Rwanda; as Primary Investigator of the Ebola Research Team for International Medical Corps (IMC), a disaster and humanitarian relief organization; and as the Director for the new Humanitarian Innovation Initiative at Brown University, whose goals are to improve the quality and professionalize the delivery of humanitarian aid worldwide. Dr. Levine also serves as the Editor-in-chief for Academic Emergency Medicine's annual Global Emergency Medicine Literature Review. His own research focuses on improving the delivery of emergency care in resource-limited settings and during humanitarian emergencies.

Research

With funding support from the NIH and private foundations, Dr. Levine has carried out a series of studies over the past seven years focused on improving the delivery of emergency care for children with acute diarrhea worldwide. His early research in Rwanda focused on assessing the performance of currently recommended international guidelines for management of diarrhea in children, including the World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) guidelines. In Bangladesh, Dr. Levine launched the twin Dehydration: Assessing Kids Accurately (DHAKA) studies, which together derived and validated the very first clinical prediction model for assessing dehydration in children with diarrhea in a resource-limited setting: the DHAKA score. Taken together, these two studies enrolled nearly 1400 children, more than all previous diagnostic studies of dehydration in children combined together, and found the DHAKA score to be both more accurate and reliable than the current IMCI guidelines.

From 2015-2016, Dr. Levine assumed the new role of Primary Investigator for IMC’s Ebola Research Team, which was established in March 2015 with the goal of collecting, aggregating, cleaning, quality checking, and analyzing this data in order to better inform the scientific and humanitarian response to future such epidemics. His research has led to the development of new tools that front-line health workers can use to predict which patients are most likely to have EVD in the context of an epidemic, as well as new technologies for monitoring severely ill patients in the high-risk zone of an ETU. Future planned research will also provide new insight into the natural history of EVD in human populations, as well as in specific subpopulations such as children and pregnant women; the interaction between EVD and other common infectious diseases, such as malaria; and the impact of fluid resuscitation on mortality in patients with EVD.

Dr. Levine has also conducted prior research on the management of traumatic injuries, both in resource-limited settings such as Rwanda and Nicaragua and during humanitarian emergencies, such as the 2011 Libyan civil war. His research has focused both on understanding the burden of injury in these contexts, as well as methods for improving delivery of care to trauma patients despite severe resource limitations.

Publications

  1. Levine AC, Glavis-Bloom J, Modi P, Nasrin S, Atika B, Rege S, Robertson S, Schmid CH, Alam NH. “External Validation of the DHAKA score and comparison to the current IMCI algorithm for the assessment of dehydration in children with diarrhoea.” Lancet Global Health, 2016.

  2. Levine AC, Shetty PP, Burbach R, Cheemalapati S, Glavis-Bloom J, Wiskel T, Kesselly JKT. “Derivation and internal validation of the Ebola Prediction Score for risk stratification of patients with suspected Ebola Virus Disease.” Annals of Emergency Medicine, 2015; 66(3): 285-93. doi:10.1016/j.annemergmed.2015.03.011.

  3. Modi P, Glavis-Bloom J, Nasrin S, Guy A, Chowa EP, Dvor N, Dworkis DA, Oh M, Silvestri DM, Strasberg S,  Rege S, Noble VE, Alam NH, Levine AC. “Accuracy of Inferior Vena Cava Ultrasound for Predicting Dehydration in Children with Acute Diarrhea in Resource-Limited Settings.” PLoS ONE, 2015; 11(1): e0146859. doi: 10.1371/journal.pone.0146859

  4. Levine AC. “Academics are from Mars, humanitarians are from Venus: Finding common ground to improve research during humanitarian emergencies.” Clinical Trials, 2016; doi: 10.1177/1740774515617935.

  5. Becker TK, Hansoti B, Bartels S, Bisanzo M, Jacquet GA, Lunney K, Marsh R, Osei-Ampofo M, Trehan I, Lam C, Levine AC, on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group. “Global Emergency Medicine: A Review of the Literature From 2015.” Acad Emerg Med 2016. doi: 10.1111/acem.12999.

  6. Modi P, Nasrin S, Hawes M, Glavis-Bloom J, Alam NH, Hossain MI, Levine AC. “Mid-upper arm circumference outperforms weight-based measures of nutritional status in children with diarrhea.” J Nutr, 2015. pii: jn209718. doi: 10.3945/jn.114.209718.

  7. Mugeni C* and Levine AC*, Munyaneza RM, Murindahabi E, Cockrell HC, Glavis-Bloom J, Nutt CT, Wagner CM, Gaju E, Rukundo A, Habimana JP, Karema C, Ngabo F, Binagwaho A. “Nationwide Implementation of Integrated Community Case Management of Childhood Illness in Rwanda.” Glob Health Sci Pract 2014; 2(3):328-341. doi: 10.9745/GHSP-D-14-00080 (* indicates co-first authors)

Teaching

Brown University DEVS 1802S: Human Security and Humanitarian Response
Directed Spring Semester Seminar Course
16 classes – 20 students

Brown International Advanced Research Institutes
Co-Convener for Institute on Humanitarian Response and Post Conflict Reconstruction
2 week course – 40 international students in attendance

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